BA-NextCage

Multimodal Home-cage Phenotyping System

AI-driven multimodal animal phenotyping platform. Real-time analysis of ten fine behaviors and 3D kinematics across multiple animals, with 24/7 home-cage monitoring, individual food and water intake tracking, and automated body temperature and weight measurements.

Multimodal Home-cage Phenotyping System

Research context

Ethology needs a longer observation window

Traditional behavioral studies often rely on short tests conducted outside the home cage. Handling and unfamiliar test settings can alter natural behavior, while manual observation add further bias. These limitations make it difficult to follow disease progression over time. They also obscure circadian activity patterns and natural social behavior. With the growing use of chronic disease models and longitudinal drug studies, researchers need low-disturbance systems that support continuous observation and provide a more natural, comprehensive view of the animal phenotype.

Behavioral snapshots

Short tests capture only fragments, missing disease progression and circadian dynamics.

Needs a continuous observation window

Identity confusion

Group-housed animals are easily misidentified, undermining individual-level tracking.

Needs stable multi-animal identity

Hard to quantify

Manual observation makes fine behaviors and social interaction noisy and hard to reproduce.

Needs objective quantification

Siloed data

Behavior, physiology, and environment stay siloed, preventing unified phenotyping.

Needs multimodal alignment

Manual review

Long-duration videos require extensive manual annotation and review.

Needs automated analysis

Poor stability

Systems struggle to maintain reliable operation during long-term experiment, disrupting longitudinal studies.

Needs reliable continuous capture

The turning point is not another monitoring cage

It is turning continuous changes in natural behavior into individual-level, computable, comparable, and traceable digital phenotypes.

Technical leadership

The first HomeCage AI platform for fine-grained behavioral phenotyping

Core technology stems from Nature Communications research. Built on 3D computer vision and multidimensional time-series analysis, the platform turns complex behavioral patterns into a computational framework for quantitative digital phenotyping, leading in technical innovation, scientific rigor, and industrialization.

AI vision & deep pose estimation

Multi-camera sync capture and 3D reconstruction enable robust tracking of joints, poses, and trajectories across species.

Ethogram-inspired computing framework

Pose → action → ethogram → state, a linguistics-inspired framework for fine behavior decoding.

Naturalistic Behavioral Phenotyping

No maze required — capture place, speed, action sequences, and subtypes in the home cage.

4th–5th Paradigms

Data- and AI-Driven 3D Vision + AI-generated ethogram

Advancing Past the 3rd Paradigm

Against Noldus and ANY-maze

Beyond the Lab

Commercial deployment vs. research-stage MoSeq

100+ Users Worldwide

Research translated into real-world adoption

Only Production-Ready 3D AI Platform

A deployable platform for animal behavior research

Product Architecture

From multimodal sensing to digital phenotyping

Sensing · Edge Intelligence · Data Hub · Application

Sensing hardware, embedded algorithms, and centralized control software are integrated, enabling multimodal acquisition, real-time AI analysis, centralized device management, and visualization reporting.

Why NextCage

Ahead of traditional activity cages across key metrics

Category
Specific indicators
Traditional observation systemsPrimarily Single-Metric Monitoring
Our systemComprehensive multi-metric analysis
Animal welfare
Multi-Animal Monitoring
Only 1
Simultaneous monitoring of 2–5 animals with stable multi-ID and fine-behavior recognition
Undisturbed Home-Cage Monitoring
Reduces stress and preserves naturalistic behavior.
Enriched environment
Running wheels, climbing structures, and other enrichment modules.
Technology methods
3D-AI technology
Patented 3D AI technology
AI quantitative observation
Real-time intelligent recognition of 8+ behaviors, reducing human error
Data dimension
Multimodal data (behavior + physiology + environment)
Multi-dimensional coverage beyond single-metric limits
Behavior parameters
Basic behaviors
Comparable coverage of basic behaviors
Fine-grained behaviors (real-time)
Enables real-time recognition of fine-grained behaviors.
Video tracking
AI-driven high-precision tracking replacing manual observation
Physiological parameters
Drinking / Feeding
Drinking bouts & volume, feeding bouts & intake
Body temperature & weight
Temperature & weight monitoring, weight accuracy to 0.1 g
Environmental parameters
Smart Monitoring of Food, Water & Environmental Conditions
Real-time food, water, and env. parameters (temp, humidity, light) with automatic alerts for animal welfare and study continuity

Core capabilities

One system, complete phenotyping—from behavior to physiology

3D Behavior

Real-time multi-animal 3D parsing

Synchronized pose and trajectory reconstruction quantifies fine-grained behavior and social interactions, making complex behavioral phenotypes computable and comparable.

24/7

Around-the-clock home-cage observation

Automated 24/7 operation for chronic models and longitudinal designs.

Diet

Smart food & water monitoring

Automatic feeding and drinking bout counts and intake with real-time anomaly alerts.

0.1 g

Automated temperature & weight

Contactless temperature trending with weight precision to 0.1 g.

FILTER BY CAPABILITY

Integrated multimodal sensing, edge AI, and visual reporting, covering fine behavior, 24/7 monitoring, and physiology.

System options

Hardware and software, configured for your study

From cage sensors to AI algorithms and visualization—deploy only the modules you need.

Hardware

Terminal hardware

  • Multi-view cameras & identity markers
  • Monitoring cages · MCU · edge compute
  • IVC · lighting · IR thermometer
  • Env. sensors (temp / humidity / light)
Terminal hardware

Software

Algorithms & software

  • Multi-animal ID & behavior recognition
  • Live monitoring · 3D reconstruction views
  • Behavior sequences & synced charts
  • Central server · OTA · high-throughput capture
Algorithms & software

Get started

Book a NextCage demo

Explore deployment options, custom configs, and research collaboration — start smart-cage phenotyping.