BehaviorAtlas

3D-AI Fine Behavior Analysis System

China's first markerless 3D animal pose capture system. Identify 16+ keypoints, quantify 40+ behavior subtypes, and export publication-ready charts — for mice, rats, NHPs, and more.

3D-AI Fine Behavior Analysis System

BehaviorAtlas Next-Gen Fine Behavior Analysis

China's first 3D-AI fine ethology product — backed by publications, patents, media coverage, and peer recognition

01

Publications

02

Patents

Behavior recognition apparatus and method, computing device and storage medium
3D animal behavior capture apparatus, method, system and application
Behavior quantification method and terminal based on states and atlas
Animal fixation device with precise head orientation adjustment
Running ball apparatus
3D animal behavior capture and recognition system

6 granted · behavior recognition · 3D capture · quantification

04

Scientist Endorsement

In a recent wild monkey behavior study, our work received an extensive dedicated commentary:

Read Original
Science Advances review excerpt
Science Advances, 2022

Prof. Andrew Zisserman

“Adopting automated behavioral recognition is scalable, increasing the speed, quantity, and detail of data that can be collected and analyzed. Once classifiers have been trained, such work can move beyond broad classification of general behavioral states (eating, resting, etc.) to include fine-grained analysis at multiple layers/dimensions of behavior.”

Related work appears in Nature family journals, with coverage from CAS, China Science Daily, CCTV, and dozens of outlets — featured as a CAS progress highlight and reviewed by China Brain Project experts.

Product Features

Combining markerless 3D capture, AI recognition, and multi-species support to unlock the full potential of 3D behavior analysis.

First

China's First 3D-AI Analysis

BayOne's proprietary markerless 3D pose capture system — full-spectrum intelligent quantitative behavior analysis for neuroscience.

China's First 3D-AI Analysis
3D

Markerless 3D Fine Analysis

Fine 3D behavior recognition for open field and other paradigms — no physical markers on animals.

Markerless 3D Fine Analysis
AI

ML & AI Powered

Deep learning identifies 16+ keypoints; ML decomposes behavior sequences and phenotypes for smarter analysis.

ML & AI Powered
Fine

Hierarchical Behavior Encoding

Hierarchical encoding: postures as letters, actions as syllables, behavior maps as sentences — quantifying every level.

Hierarchical Behavior Encoding
FOV

4+ Camera Array

Multi-camera arrays capture activity from all angles, solving occlusion in single-view 2D recording.

4+ Camera Array
Rich

40+ Behavior Subtypes

AI automatically extracts and quantifies 40+ fine subtypes including sniffing, climbing, jumping, and standing.

40+ Behavior Subtypes
Data

100+ Quantified Parameters

39 kinematic parameters plus distributions across 40 action types — multi-dimensional phenotypic data.

100+ Quantified Parameters
Pub-ready

Publication-Ready Visualization

Export bar charts, heatmaps, clustering, dimensionality reduction, and behavior spectra — ready for SCI publication.

Publication-Ready Visualization

Product Comparison

Traditional 2D analysis: quantifies only a handful of behaviors

Severe information loss — fails to capture real behavior

Single-view capture — prone to occlusion
Single-view capture — prone to occlusion

When body parts occlude each other or overlap with cage walls and equipment edges, keypoint and contour detection is easily lost, reducing analysis stability.

Centroid / outline tracking only
Centroid / outline tracking only

Tracking relies only on centroids or outlines — limited behavioral dimensions, unable to capture posture changes, limb motion, or complex behavior structure.

Low behavior-type resolution
Low behavior-type resolution

Many behaviors look similar in top-down view — immobility, sniffing, grooming, mild exploration — and are easily misclassified or merged into one category.

Basic parameter output
Basic parameter output

Outputs only simple metrics such as distance, speed, dwell time, and zone entries — insufficient to capture complex behavioral changes.

BehaviorAtlas 3D-AI: rich behavioral information

Fine-grained, comprehensive, objective behavior characterization

Multi-view synchronized capture
Multi-view synchronized capture

Multi-camera synchronized capture from different angles reduces single-view occlusion and information loss for more complete locomotion data.

3D skeleton reconstruction
3D skeleton reconstruction (16+ points)

Reconstructs 3D skeletons from multi-view video — accurately restoring spatial position and posture of head, trunk, limbs, and tail.

Behavior recognition & decomposition
Behavior recognition & decomposition

Powered by BehaviorAtlas decomposition — automatically segments continuous video into behavior episodes and types for fine-grained spectrum analysis.

Multi-dimensional output
Multi-dimensional output

Beyond speed, distance, and time — quantifies posture, joint angles, body height, trajectories, behavior proportions, temporal dynamics, and more.

Recommended

BehaviorAtlas

Spatial DimensionFull 3D spatial resolution
AccuracyHigh (mm-level)
AutomationSemi-automated with minimal manual input
AlgorithmAI pose estimation models
Body Resolution16 body keypoints
Behavior Granularity40 fine subtypes + rich kinematics
MetricsExtensive custom metrics
VisualizationDeep multi-dimensional views
ReproducibilityHigh — stable and objective
Legacy

Traditional 2D Software

Spatial DimensionLimited 2D plane view
AccuracyModerate — occlusion-prone
AutomationSemi-automated — more manual work
AlgorithmBackground subtraction, threshold tracking
Body ResolutionNone / centroid only
Behavior GranularityBasic kinematic parameters
MetricsBasic movement metrics only
VisualizationBasic 2D tracks / heatmaps
ReproducibilityHigh
Traditional

Manual Observation

Spatial DimensionNaked-eye 2D or limited 3D
AccuracyHigh subjective error, poor reproducibility
AutomationFully manual recording
AlgorithmVisual observation — no algorithm
Body ResolutionNone
Behavior GranularityVery limited
MetricsMinimal — time-consuming
VisualizationNo automated visualization
ReproducibilityLow — hard to reproduce

Product Matrix

Multi-species solutions from rodents to primates for comprehensive behavior research.

Mice & RatsMice & Rats

Mice & Rats

Fine behavior analysis for mice and rats — supporting disease models, drug screening, and mechanism studies.

BA - 3D Mouse 02 (aka DC02)
Activity space: 50×50×50 cm

3D Skeleton Reconstruction:4-camera sync capture with multi-view 3D reconstruction — mm-level accuracy with occlusion handling.

Advanced Deep Learning:Identifies 16 keypoints across body, limbs, head, and tail — deep learning trained on large-scale experimental data for stable pose estimation.

Rich Application Support:Supports disease model characterization, behavior modulation, and efficacy evaluation.

Core Software Suite

C
Capture Acquisition SoftwareMulti-camera synchronized capture with visible/IR modes and TTL event sync.
A
Analyzer Processing SoftwareAI multi-keypoint detection, 3D skeleton reconstruction, and automated behavior extraction.
E
Explorer Visualization SoftwareRich charts and behavior spectrum previews with multi-dimensional data export.

Explore full capabilities, workflows, and multi-species solutions in the 3D-AI Fine Behavior Software Suite

Standard Product
Standard integrated hardware/software system — available for direct purchase and rapid deployment.
AI Fine Behavior Analysis
Built-in AI identifies 16+ body points, 40+ behavior subtypes, and publication-ready charts.
Professional Deployment
Our senior engineers provide on-site installation, software training, and full-cycle analysis support.

Multi-Species Solution Matrix

Img
Mice & Rats
Img
Non-human Primates
Img
Canine
Img
Porcine
Img
Poultry
Img
Tree Shrew
Model
BA - 3D Mouse 02aka DC02
BA - 3D NHP 01
BA - 3D Canine 01
BA - 3D Pig 01
BA - 3D Chicken 01
BA - 3D Tree Shrew 01
Cameras459964
Activity Space50×50×50 cm1.1×1.1×1.1 m5×5×2.9 m4×4×2.9 m1.5×1.5×2 m1×1×1 m
Commercial StatusStandard ProductStandard ProductCustom SolutionCustom SolutionCustom SolutionCustom Solution
Case VolumeHighHighMediumMediumMediumMedium
Typical Applications
Disease ModelsDrug ScreeningMechanism Research
Disease CharacterizationBrain Circuit ResearchPreclinical Evaluation
Motor ControlNeural CircuitsNeural Injury Recovery
Neural InjurySurgical RecoveryAnimal Science
Livestock ScienceBionics ResearchAnimal Welfare
Neuropsychiatric ModelsNeural MechanismsAnimal Evolution

Research Impact

Real-world application data and research outcomes of BehaviorAtlas 3D-AI across global scientific settings.

BAYONE LIFE TECH

DASHBOARD v2.0

Overview

LIVE
Published Papers (Total)
51papers
Pending Papers
10
Disease Types
30+
Analysis Runs
300+
Animal Samples
2w+
Analysis Samples
1w+
Species Supported
7

Publication Trend

10 papers pending publication

+50% YOY
202120222023202420252026

Animal Species

Mouse
Mouse
Rat
Rat
Tree Shrew
Tree Shrew
Dog
Dog
Pig
Pig
Monkey
Monkey
Chicken
Chicken

Published SCI Papers

32
  • #01Signal Transduction and Targeted Therapy
  • #02Cell Research
  • #03Nature Aging
  • #04Nature Machine Intelligence
  • #05Neuron
  • #06Nature Communications
  • #07Autophagy
  • #08Advanced Science
  • #09Theranostics
  • #10Journal of Advanced Research
  • #11Science Advances
  • #12Research
  • #13Journal of Neuroinflammation
  • #14Molecular Psychiatry
  • #15Advanced Healthcare Materials
  • #16npj Parkinson's Disease
  • #17Brain, Behavior, and Immunity
  • #18Cell Reports
  • #19Fundamental Research
  • #20Translational Psychiatry
  • #21Neuroscience Bulletin
  • #22Cell Proliferation
  • #23Communications Biology
  • #24BMC Biology
  • #25The FASEB Journal
  • #26Frontiers in Psychiatry
  • #27Cognitive Neurodynamics
  • #28Addiction Biology
  • #29Frontiers in Integrative Neuroscience
  • #30Biochemical and Biophysical Research Communications
  • #31European Journal of Neuroscience
  • #32Journal of Translational Genetics and Genomics
Research Topics
AutismFearParkinson's DiseaseSpinal Cord InjuryAddictionDepressionAnxietyPostoperative DeliriumAgingHuntington's DiseaseAcute StressPTSDAnesthesiaPainPain-Anxiety ComorbidityStressHuntington ChoreaCerebral IschemiaSurvival ThreatAddictive DrugsPsychiatric DrugsAnesthetic Drugs
Client Institutions
Peking UniversityTsinghua UniversityFudan UniversityShanghai Jiao Tong UniversityZhejiang UniversityStanford UniversityThe University of Hong KongSIATXijing HospitalPuling Bio

Application Cases

Real-world research cases powered by BehaviorAtlas 3D-AI — spanning autism, anxiety, depression, Parkinson's, Alzheimer's, and acute stress models.

Fine postural dynamics reveal potential autism behavioral markers

Autism model mouse behavioral marker identification

Fine postural dynamics reveal potential autism behavioral markers

Fine postural dynamics analysis uncovered potential behavioral markers in autism model mice, offering a new quantitative lens for model assessment.

Huang, Kang et al. Nature Communications 2021

Published with BAYONE products
A new perspective on animal anxiety assessment

Reassessing anxiety-like behavior

A new perspective on animal anxiety assessment

3D behavioral analysis reassesses anxiety-like behavior, unbiasedly identifying novel biomarkers that complement classical paradigms; fine-grained profiling separates all 20 stressed from control mice where classic anxiety metrics fail.

Liu, Nan et al. BBRC 2021

Published with BAYONE products
AI decodes spontaneous behavior under different stressors

Systematic depression-like behavior assessment

AI decodes spontaneous behavior under different stressors

Forced swim tests show depressive-like behavior across stress models; AI fine spontaneous profiling reveals shared and distinct changes — CRS and CSDS mice both show more rearing and less rotation.

Tseng, Yuting et al. Translational Psychiatry 2023

Published with BAYONE products
Abnormal spontaneous behavior in PD mice

Parkinson's disease mouse behavioral profiling

Abnormal spontaneous behavior in PD mice

Systematic PD mouse profiling with 3D multi-view capture and machine learning precisely captures spontaneous behavioral differences in MPTP models for sensitive model validation and therapeutic assessment.

Zhong, Hao et al. Translational Psychiatry 2025

Published with BAYONE products
Capturing spontaneous behavior differences in AD mice

Alzheimer's disease mouse behavioral profiling

Capturing spontaneous behavior differences in AD mice

Open-field profiling of AD pathological models captures abnormal walking, fast exploration, and slow exploration — offering a new perspective for model establishment and drug efficacy evaluation.

Miller, Stephanie R et al. Cell Reports 2024

Acute stress mice show unique behavioral subtypes

Acute stress mouse behavioral profiling

Acute stress mice show unique behavioral subtypes

Systematic profiling of acute stress mice reveals unique spontaneous behavior patterns and action subtypes distinct from controls.

Ye, Jialin et al. Cell Reports 2025

Published with BAYONE products

User Papers

View More

Selected publications powered by our 3D-AI system — supporting teams in publishing 50+ high-impact papers in Nature Aging, STTT, and other top journals.

Breakthrough in Parkinsonian visual hallucination research with BayONE support

Breakthrough in Parkinsonian visual hallucination research with BayONE support

Nanjing Medical University's Feng Han team used BayONE products to identify key biomarkers, transforming complex hallucination symptoms into quantifiable animal behavioral phenotypes, published in Signal Transduction and Targeted Therapy.

STTT (IF=52.7)
Read More
Stem cell vesicles reverse aging in macaques

Stem cell vesicles reverse aging in macaques

Jinghui Huang's team at Air Force Medical University evaluated antler blastema progenitor cells in mice and macaques, using the 3D fine behavior analysis system to precisely quantify dynamic changes in motor function during aging intervention.

Nature Aging (IF=19.4)
Read More
Behavioral and neural mechanisms of social homophily in opioid addiction

Behavioral and neural mechanisms of social homophily in opioid addiction

Sun Linlin's team at Peking University Health Science Center published in Neuron, revealing social homophily in opioid-addicted animals and the underlying neural mechanisms.

Neuron (IF=15)
Read More
AI fine behavior reveals fast DNA replication forks drive anxiety

AI fine behavior reveals fast DNA replication forks drive anxiety

Shi Lei's team at Kunming Institute of Zoology linked DNA replication fork speed to neurobehavior, showing that embryonic replication dysregulation profoundly affects adult brain function and anxiety-like behavior.

Nature Communications (IF=14.7)
Read More
New mechanism of S-ketamine therapy for PTSD

New mechanism of S-ketamine therapy for PTSD

Zhao Guangchao's team at Xijing Hospital used AI-assisted fine behavior analysis to quantify PTSD core symptoms and revealed the time-dependent therapeutic effects of S-ketamine.

Advanced Science (IF=14.1)
Read More
Unraveling spontaneous self-injurious behavior in macaques

Unraveling spontaneous self-injurious behavior in macaques

Jianhong Wang's team at Kunming Institute of Zoology found that spontaneously self-injurious macaques show low activity, social deficits, circadian rhythm abnormalities, and aberrant emotional-defensive responses through fine behavioral profiling.

Research (IF=10.7)
Read More
Lifelong nicotine dynamically modulates age-related motor and metabolic aging in mice

Lifelong nicotine dynamically modulates age-related motor and metabolic aging in mice

Xin'an Liu's team at SIAT Brain Institute used fine behavior analysis across a lifelong oral nicotine paradigm, showing that lifelong nicotine intervention alleviates motor decline and yields a biologically younger behavioral phenotype in mice.

Advanced Science (IF=14.1)
Read More
BehaviorAtlas reveals Scn2a loss drives autism-like behavior

BehaviorAtlas reveals Scn2a loss drives autism-like behavior

Shu Yousheng's team at Fudan University used BayONE products to show that Scn2a loss in VTA dopamine neurons causes hyperactivity, repetitive stereotypy, and loss of social novelty preference — hallmark autism-like phenotypes.

Neuron (IF=15)
Read More
Tooth pain drives anxiety? AI fine analysis decodes comorbid phenotypes

Tooth pain drives anxiety? AI fine analysis decodes comorbid phenotypes

Jing Huang's team at Air Force Medical University used longitudinal 3D behavior profiling to map craniofacial structural deficits to neurobehavioral dysfunction, showing mandibular asymmetry drives progressive hyperalgesia and anxiety-like behavior in mice.

Advanced Science (IF=14.1)
Read More