AI-Powered In Vivo Phenomicsfor Neuroscience and CNS Drug Discovery
Turning multimodal animal data into translational evidence for preclinical R&D.
1. DATA ACQUISITION
BA-nextCage™ multimodal home-cage monitoring
2. MULTIMODAL PHENOTYPING
Video, physiology, metabolism and environment
3. AI BEHAVIOR ANALYTICS
Pose, motifs, phenotypes and dynamics
4. BIOLOGICAL INSIGHTS
Disease signatures and treatment effects
5. TRANSLATIONAL DECISION-MAKING
Evidence for candidate selection and pipeline prioritization
2026.07.02 Good news! BayOne · AI-powered high-precision animal behavior analysis for biopharma selected as MIIT AI Application Showcase Case
2026.06.12 BayOne hosts Greater Bay Area symposium on multi-species brain disease models & intelligent behavioral phenotyping
2026.06.01 BayOne surpasses 200 partner institutions, supporting 50+ publications
2026.05.25 BayOne named Outstanding Science Popularization Unit in Huangpu District, Guangzhou
2026.05.22 SUAT undergraduates visit BayOne to advance teaching & practice collaboration
2026.04.09 EthoAI cloud platform for animal behavior analysis goes live
2026.03.30 EthoClaw — the first neuroethology lobster AI agent
2026.01.29 BayOne wins Excellence Award at the 14th China Innovation & Entrepreneurship Competition (Guangzhou, Pharma R&D)
2026.01.01 Illuminating data, moving forward — BayOne 2025 annual report
2025.11.26 BayOne at SfN 2025 — Society for Neuroscience Annual Meeting
MOTIVATION
BayOne · Paradigm Shift
From traditional phenotyping to AI-powered decision support for preclinical CNS R&D.
YEAR 0
YEAR 6
YEAR 12+
Target Validation
Compound Screening
Lead Optimization
Preclinical
Preclinical Stage (Years 3–5)
Phase I
Phase II
Phase III
💊Approval
Traditional Phenotyping
Manual observation. Limited resolution. Weak decision support.
AI Precision Phenotyping
High-resolution behavioral signatures for preclinical decision-making.
TECHNOLOGY ROADMAP
From Perception to Decision Intelligence
Building brain–behavior AI systems for multimodal phenotyping and CNS drug discovery.
PHASE 0
Scientific Questions & Experimental Contexts
From disease models to multimodal data requirements.
RESEARCH QUESTIONSEfficacy and safety questions for CNS drug candidates
BEHAVIORAL ASSESSMENTBehavioral and motor assessment in home-cage conditions
DISEASE MODELSStress, social isolation, neurodevelopmental and neurodegenerative models
ANIMAL MODELSMice, rats, and genetically modified lines
SOLUTIONS
BayOne · Business Matrix
Connecting research instruments, preclinical services, and AI analytics into a full-stack phenotyping platform.
Research Instruments
BehaviorAtlas Algorithm Platform
Built on proprietary AI and animal technology, the BehaviorAtlas instrument suite, AI software, and cloud platform deliver precise behavior tracking and multi-dimensional quantification for neuropsychiatric research and drug evaluation.
1Millisecond Capture & 3D Reconstruction
Advanced computer vision for sub-millisecond capture and 3D spatial reconstruction.
2Capture-to-Visualization Pipeline
End-to-end automation from acquisition to analysis and visualization.
3Multi-layer Kinematic & Behavioral Atlas
Multi-dimensional kinematic and behavioral analysis with comprehensive atlas reports.
ACADEMIC IMPACT
High-Impact Research Enabled by BayOne
From multi-species behavior analysis to complex disease models, BayOne technologies enable high-impact neuroscience research.
AutismSpinal Cord InjuryParkinson's DiseaseDepressionAddictionFearAnxietyPostoperative DeliriumAcute StressPTSDPainPain-Anxiety ComorbidityStressCerebral IschemiaAgingHuntington's DiseaseHuntington ChoreaAnesthesiaSurvival ThreatAddictive DrugsPsychiatric DrugsAnesthetic Drugs
2021.05.13 Co-founder Dr. Huang Kang publishes in a Nature sister journal
2021.06.25 Objective, comprehensive reassessment of anxiety-like behavior
2021.10.22 Altered eye-movement traits in gene-knockout mice
2022.03.01 Innovative integration of behavior with freely moving two-photon imaging
2022.03.24 Co-founder Dr. Huang Kang publishes mobile mouse eye-tracking system paper
2022.04.06 Pupil dynamics during wakefulness across sleep states in mice
2022.12.15 Sex differences in mouse survival-threat coping strategies
2023.05.25 New advances in depression-like behavior research
2023.08.02 Fine behavior reveals dexmedetomidine may prevent postoperative delirium
2023.10.17 Pupil anomalies identified in autism model dogs
2024.01.08 Algorithm lead Chen Ke publishes in a Nature sister journal
2024.05.24 Intelligent recognition of mouse stress-level behavior
2024.06.20 Sex-specific neurobehavioral profiles in autism model mice
2024.07.17 Linking social memory with whisker-related sensory perception
2024.10.21 Pupil tracking enables more precise fear assessment
2025.02.25 SIAT identifies spontaneous behavior anomalies in acute-stress mice
2025.03.11 Early anesthesia closely linked to social deficits
2025.04.03 Spontaneous behavior anomalies newly found in Parkinson model mice
2025.04.09 AI decodes arecoline "addiction phenotypes"
2025.04.16 Electroacupuncture may reduce olanzapine side effects
2025.05.09 Eye-movement patterns under repeated visual threat in mice
2025.07.10 Fudan University: SCN2A loss induces autism-like behavior
2025.07.14 Nature Aging breakthrough: deer antler stem-cell exosomes slow aging
2025.07.21 Behavioral phenotyping in transgenic mice
2025.07.28 Nicotine dynamically modulates motor phenotypes
2025.07.31 Unraveling spontaneous self-injury in macaques
2025.08.16 A new path for preventing postoperative delirium
2025.09.12 Peking University reveals neural basis of drug-addiction social bonding
2025.09.23 How is fear encoded? New neural mechanisms uncovered
2025.09.24 New findings on orofacial pain–emotion comorbidity
2025.09.25 Xijing Hospital reveals S-ketamine mechanism for PTSD
2025.11.18 KIZ finds fast DNA replication can drive anxiety
2025.11.24 New behavior patterns directly linked to visceral pain
2025.11.26 Shanghai University quantifies Parkinson motor symptoms and drug response
2025.12.21 Caffeine shifts reward preference and behavior patterns
2026.02.04 Key mechanisms of neuronal injury and gait recovery after spinal cord injury
2026.02.10 Critical signaling pathway for motor recovery after spinal injury
2026.02.11 Bone–brain crosstalk regulates rapid visual escape survival behavior
2026.02.18 SJTU deep analysis of postoperative pain in mice
2026.03.07 Mechanisms improving motor function after spinal cord injury
2026.03.25 Southwest Hospital precisely assesses recovery after cerebral ischemia
2026.04.04 Peking University: cocaine reduces threat perception
2026.04.22 STTT landmark paper advances Parkinson visual hallucination research
ACHIEVEMENTS
BayOne · Industry Recognition
Defining industry standards in neurobehavioral analysis and phenomics through credentials and major provincial programs
Honors & Credentials
High-Tech Enterprise
National High-Tech Enterprise Certification
Tech SME
Guangdong Tech SME Certification
Provincial Major Projects
Participant in Guangdong Key R&D Programs
Top Journals
2 Nature family publications
Global Presence
SfN 2024 / CNS 2025 / Drug Toxicology Meeting
National AI Application Case Study
Selected among MIIT 2025 AI Application Typical Cases
Provincial Quality High-Tech Product
Company products recognized at Guangdong provincial level in 2026
SPF-Level Animal Facility Full Qualification
Laboratory animal use and production licenses
Life Sciences 1st Place
"Dream China · Zhihui Jiashan" Innovation Competition
Ecosystem & Joint R&D
BayOne × CAS Shanghai Institute of Neuroscience
Automated fine motor assessment for rodents — multi-dimensional behavior capture beyond single-paradigm limits.
BayOne × prisysbiotech
NHP behavioral phenotyping for CNS drug screening and lead compound development.
BayOne × TRANSCEND
Two-photon + behavior joint analysis — synchronized fine behavior and neural activity in freely moving animals.
Core Intellectual Property
0
Core Invention Patents
0
Software Copyrights
0
Proprietary Core Algorithms
Invention PatentBehavior recognition apparatus and method, computing device and storage medium
Invention Patent3D animal behavior capture apparatus, method, system and application
Invention PatentBehavior quantification method and terminal based on states and atlas
Utility Model PatentAnimal fixation device with precise head orientation adjustment
Utility Model PatentRunning ball apparatus
Software CopyrightBehaviorAtlas Analyzer Software V1.0.1
Software CopyrightBehaviorAtlas Explorer Software V1.0.0
Software CopyrightBehaviorAtlas® 3D-AI Mouse Behavior Capture Software V2.0.0
Software CopyrightBehaviorAtlas® 3D-AI Non-human Primate Behavior Capture Software V1.0.0
Software CopyrightBehaviorAtlas® 3D-AI Non-human Primate Behavior Data Processing Software V1.2.0
Software CopyrightBehaviorAtlas® 3D-AI Non-human Primate Behavior Visualization Software V1.2.0
Software CopyrightBehaviorAtlas® 2D-AI Mouse Behavior Tracking Software V1.0.0
Software CopyrightBehaviorAtlas® Pose Labeler Software V1.0.0
Software CopyrightBehaviorAtlas® 3D-AI Mouse Motor Function Capture Software V1.0.2
Software CopyrightBehaviorAtlas® 3D-AI Mouse Motor Function Analysis Software V1.0.1
Software CopyrightBehaviorAtlas® Eye-tracking Capture Software for Freely-moving Mouse V1.0.0
Software CopyrightBehaviorAtlas® Eye-tracking Analysis Software for Freely-moving Mouse V1.0.0
Software CopyrightBehaviorAtlas® Eye-tracking Capture Software for Head-fixed Mouse V1.2.0
Software CopyrightBehaviorAtlas® Mouse Virtual Reality Control Software V1.0.0
Software CopyrightBehaviorAtlas ScratchScope NHP Software V1.0.0_01
Software CopyrightBehaviorAtlas® 3D-AI Mouse Behavior Capture (Pro) Software V1.0.0_01
Software CopyrightBehaviorAtlas® AI Mouse Face Analysis Software V1.0.0_01
Software CopyrightBehaviorAtlas® Behavioral Movement Rule Extraction Tool Software V1.0.0_01
Software CopyrightBehaviorAtlas® Mouse Realtime Behavioral Analysis Software V1.0.0_01
Software CopyrightBehaviorAtlas® Mouse Optomotor Capture Software V1.0.0_01
A coordinated three-hub network
Connecting R&D, experimentation, and industrial translation